产品名称:
CD146
产品货号:
PLD-49
别名 :
CD146; MUC18
实验类型 :
IHC-P
反应种属 :
Human
宿主物种 :
Rabbit
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背景
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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细胞定位
细胞膜
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基因 ID
4162
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Swiss Prot
P43121
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别名
CD146; MUC18
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反应种属
Human
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实验类型
IHC-P
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推荐稀释比
1:500-1:2000
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宿主物种
Rabbit
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克隆性
Monoclonal
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同位型
IgG
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纯化方式
Affinity Purification
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偶联物
Un-conjugated
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储存条件
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.