产品名称:
Factor Illa
产品货号:
PLD-57
别名 :
TF; TFA; CD142
实验类型 :
IHC-P
反应种属 :
Human
宿主物种 :
Rabbit
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背景
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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细胞定位
细胞膜
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基因 ID
2152
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Swiss Prot
P13726
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别名
TF; TFA; CD142
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反应种属
Human
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实验类型
IHC-P
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推荐稀释比
1:500-1:1000
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宿主物种
Rabbit
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克隆性
Monoclonal
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同位型
IgG
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纯化方式
Affinity Purification
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偶联物
Un-conjugated
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储存条件
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.