产品名称:
OTX2
产品货号:
PLD-847
别名 :
CPHD6; MCOPS5
实验类型 :
IHC-P
反应种属 :
Human
宿主物种 :
Rabbit
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背景
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
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细胞定位
细胞核
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基因 ID
5015
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Swiss Prot
P32243
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别名
CPHD6; MCOPS5
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反应种属
Human
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实验类型
IHC-P
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推荐稀释比
1:200
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宿主物种
Rabbit
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克隆性
Monoclonal
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同位型
IgG
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纯化方式
Affinity Purification
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偶联物
Un-conjugated
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储存条件
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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