产品名称:
TG/Thyroglobulin
产品货号:
PLD-98
别名 :
TGN; AITD3
实验类型 :
IHC-P
反应种属 :
Human
宿主物种 :
Rabbit
-
背景
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
-
细胞定位
细胞质
-
基因 ID
7038
-
Swiss Prot
P01266
-
别名
TGN; AITD3
-
反应种属
Human
-
实验类型
IHC-P
-
推荐稀释比
1:500-1:1000
-
宿主物种
Rabbit
-
克隆性
Monoclonal
-
同位型
IgG
-
纯化方式
Affinity Purification
-
偶联物
Un-conjugated
-
储存条件
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
浙公网安备33010602014168号